CHARLOTTE, N.C. (AP) — Cam Newton threw three touchdown passes and ran for another, and Carolina sacked Eli Manning seven times as the Panthers handed Tom Coughlin his worst defeat as coach of the New York Giants, 38-0 Sunday.
It was the largest margin of victory in Panthers history.
The Giants are in trouble: Of the 161 teams that have started the season 0-3 since 1978, only five made the NFL playoffs, according to STATS LLC.
BEARS 40, STEELERS 23: PITTSBURGH (AP) — Chicago’s defense forced five turnovers and scored twice, and the Bears beat Pittsburgh to remain unbeaten.
Major Wright returned an interception 38 yards for a touchdown in the second quarter, and Julius Peppers picked up Ben Roethlisberger’s fumble and raced 42 yards for a score in the fourth quarter as the Bears (3-0) held off a late rally.
PATRIOTS 23, BUCCANEERS 3: FOXBOROUGH, Mass. (AP) — Tom Brady threw two touchdown passes to Kenbrell Thompkins to lead New England to a one-sided win over Tampa Bay.
Thompkins, an undrafted free agent, scored on plays of 16 and 5 yards in the first half. Aaron Dobson, a second-round draft pick, finished with seven catches for 52 yards. In their first two games, the rookies combined for just nine receptions.
BENGALS 34, PACKERS 30: CINCINNATI (AP) — Terence Newman returned a fumble 58 yards for a touchdown with 3:47 left, rallying Cincinnati past Green Bay in a game of wild momentum swings set up by nonstop turnovers.
SAINTS 31, CARDINALS 7: NEW ORLEANS (AP) — Drew Brees passed for three scores and scrambled for New Orleans’ first touchdown rushing of the season in a victory over Arizona.
The Saints quarterback was 29 of 46 for 342 yards, with two TD strikes to tight end Jimmy Graham and the other to Robert Meachem.
COWBOYS 31, RAMS 7: ARLINGTON, Texas (AP) — DeMarco Murray ran for 175 yards and a touchdown two years after torching St. Louis with a franchise record as a rookie, and Tony Romo threw for three scores in Dallas’ rout.
Murray had his first 100-yard game in more than a year.
The Cowboys (2-1) sacked Sam Bradford four times in the first half and had six overall after St. Louis (1-2) hadn’t allowed a sack in four games, dating to last season. It was the Rams’ longest streak since John Hadl was under center for a division champion in 1973.
RAVENS 30, TEXANS 9: BALTIMORE (AP) — Daryl Smith had a 37-yard interception return for a TD, Tandon Doss took a punt 82 yards for another score, and Baltimore smothered Houston’s high-powered offense.
The Ravens (2-1) won despite playing without Ray Rice for the first time since 2008. The three-time Pro Bowl running back was replaced by Bernard Pierce, who ran for 65 yards and a touchdown.
LIONS 27, REDSKINS 20: LANDOVER, Md. (AP) — Matthew Stafford completed 25 of 42 passes for 385 yards with two touchdowns and one interception, and Calvin Johnson and Nate Burleson both had 100 yards receiving for Detroit, which beat Washington on the road for the first time.
The Lions (2-1) ended a 21-game streak against the Redskins, the second-longest in NFL history. Detroit’s last win away from home in the series came in 1935 against the Boston Redskins, two years before the move to Washington.
TITANS 20, CHARGERS 17: NASHVILLE, Tenn. (AP) — Jake Locker helped Tennessee end a skid against the San Diego that spanned two states and two decades.
Locker threw a 34-yard touchdown pass to rookie Justin Hunter with 15 seconds left and the Titans rallied to beat the Chargers.
It was their first win over the Chargers for the franchise since 1992 when the team was in Houston and Titans coach Mike Munchak still was playing for the then-Oilers.
The Titans (2-1) had lost nine straight to San Diego.
BROWNS 31, VIKINGS 27: MINNEAPOLIS (AP) — Jordan Cameron caught three touchdown passes, including the go-ahead grab in the back of the end zone with 51 seconds left, and Cleveland kept Minnesota winless.
SEAHAWKS 45, JAGUARS 17: SEATTLE (AP) — Russell Wilson matched his career high with four touchdown passes — two each to Sidney Rice and Zach Miller — and Seattle overwhelmed Jacksonville.
DOLPHINS 27, FALCONS 23: MIAMI GARDENS, Fla. (AP) — Ryan Tannehill lobbed a 1-yard touchdown pass to rookie Dion Sims with 38 seconds left, and unbeaten Miami rallied past Atlanta.
JETS 27, BILLS 20: EAST RUTHERFORD, N.J. (AP) — Geno Smith threw two touchdown passes, including a go-ahead 69-yarder to Santonio Holmes in the fourth quarter, and the New York Jets overcame a team-record 20 penalties to hang on and beat Buffalo in an ugly game.