HOUSTON (AP) — Peyton Manning owns the NFL record for touchdown passes in a season and the Denver Broncos own the AFC West title.

Manning regained his record with 51 when he threw for 400 yards and four touchdowns, including three in the fourth quarter. He surpassed the 50 TD passes Tom Brady threw in 2007 and led the Broncos (12-3) to a 37-13 win over the Texans (2-13) that extended Houston’s franchise-record skid to 13 games.

Manning did it on a 25-yard pass to Julius Thomas with 4:28 remaining. Just 2 ½ minutes earlier, he tied the mark with a 20-yard pass to Eric Decker.

He entered the game with 47 and his first touchdown came on a 36-yard pass to Demaryius Thomas in the second quarter. The second was a 10-yard throw to Decker earlier in the fourth period.

Manning had previously established the record by throwing 49 touchdown passes in 2004.

The Broncos already had a spot in the playoffs, but their victory, combined with Kansas City’s loss to Indianapolis, gave them the division crown. They could secure home-field advantage throughout the playoffs if New England doesn’t win its late game at Baltimore.

PANTHERS 17, SAINTS 13: CHARLOTTE, N.C. (AP) — Cam Newton threw a 14-yard touchdown pass to Domenik Hixon with 23 seconds left to lift the Panthers to the team’s first playoff berth since 2008. Carolina (11-4) can wrap up the NFC South and a first-round bye with a win next Sunday at Atlanta.

The Panthers intercepted Drew Brees twice and sacked him six times to avenge a 31-13 loss two weeks ago.

BENGALS 42, VIKINGS 14: CINCINNATI (AP) — Vincent Rey returned an interception 25 yards for a touchdown as Cincinnati clinched the AFC North. Andy Dalton threw four touchdown passes.

The Bengals (10-5) remained perfect at home and secured an unprecedented third straight playoff appearance when Miami lost at Buffalo. Then the Bengals won the division when the Ravens fell to the Patriots.

In his past four home games, Dalton has thrown for five, three, three and four touchdowns. The Bengals have topped 40 points in each of their past four home games, a club record.

CARDINALS 17, SEAHAWKS 10: SEATTLE (AP) — Carson Palmer overcame four interceptions to throw a 31-yard touchdown to Michael Floyd with 2:13 left. The Cardinals kept their postseason hopes going while snapping the Seahawks 14-game home win streak.

Arizona (10-5) had to win after Carolina beat New Orleans. And the Cardinals did thanks to a stingy defense that flustered Russell Wilson into one of his worst days as a pro, delaying any celebration of an NFC West championship. The Seahawks can still clinch the NFC West with a win over St. Louis next Sunday.

PATRIOTS 41, RAVENS 7: BALTIMORE (AP) — Logan Ryan had two interceptions, LeGarrette Blount scored twice and the Patriots ended the Ravens’ four-game winning streak.

The previous time these two teams met, the AFC title hung in the balance and Baltimore used a strong second half to pull out a 28-13 victory. In this one, New England took a 17-0 lead early in the second quarter and never let up behind a defense that forced four turnovers and had four sacks.

STEELERS 38, PACKERS 31: GREEN BAY, Wis. (AP) — Le’Veon Bell ran for a 1-yard touchdown with 1:28 left, then Pittsburgh withstood Green Bay’s last throw into the end zone and dealt the Packers’ playoff hopes a blow.

It’s a long shot, but the Steelers (7-8) are still mathematically in the hunt for an AFC wild-card spot. They need a lot of help.

The loss meant Green Bay (7-7-1) needed Chicago to lose at Philadelphia on Sunday night to stay in playoff contention.

Bell’s TD came soon after scrambling Packers quarterback Matt Flynn fumbled while being tackled by Troy Polamalu. The Steelers recovered at the Packers 17 and scored five plays later.

EAGLES 54, BEARS 11: PHILADELPHIA (AP) — Nick Foles threw two touchdown passes, LeSean McCoy ran for two scores and Philadelphia routed Chicago in a matchup of first-place teams with opposite stakes.

Chicago’s loss sets up two winner-take-all games for NFC division crowns next week.

The Bears (8-7) came in needing a win to clinch the NFC North and secure the No. 3 seed while Philadelphia was just trying to stay healthy. But the Eagles (9-6) played like the team trying to lock up a playoff berth.

Now, the Bears must tie or beat the Packers (7-7-1) at home next week to win the North.

COLTS 23, CHIEFS 7: KANSAS CITY, Mo. (AP) — Andrew Luck threw for 241 yards and a touchdown, Donald Brown ran 51 yards for another score in a potential preview of an AFC wild-card game.

The Colts (10-5), who have already wrapped up the AFC South, took advantage of four turnovers by the Chiefs (11-4) to win for the fifth time in their last six tries against Kansas City.

If Indianapolis ends up as the No. 4 seed in the playoffs — the Chiefs are assured the fifth seed — the teams will meet again in the warmer environs of Lucas Oil Stadium.

BILLS 19, DOLPHINS 0: ORCHARD PARK, N.Y. (AP) — The Dolphins had a three-game winning streak snapped and are in jeopardy of missing the playoffs for a fifth consecutive season. With the loss, Miami (8-7) needs help from other teams. Miami hosts the New York Jets next weekend.

The Dolphins’ loss clinched the AFC East for New England.

Kyle Williams had two of Buffalo’s season-best seven sacks to key a stifling defensive performance.

Fred Jackson had 111 yards rushing and scored on a 9-yard run, while the Bills limited the Dolphins to a season-low 103 yards and six first downs. The Bills (6-9) closed their home schedule with seven sacks for 56 this season, breaking their previous high of 50 during a 14-game season in 1964.

COWBOYS 24, REDSKINS 23: LANDOVER, Md. (AP) — Tony Romo recovered from a bad interception and rallied the Cowboys from a nine-point, fourth-quarter deficit. He found DeMarco Murray for a 10-yard touchdown pass on fourth down with 1:08 remaining.

The victory ended a two-game Dallas skid — as well as a five-game December losing streak — and sets up a winner-take-all regular season finale for the NFC East title next week, when the Cowboys (8-7) host the Philadelphia Eagles.

GIANTS 23, LIONS 20, OT: DETROIT (AP) — Josh Brown’s 45-yard field goal on the third drive of overtime lifted the Giants and knocked the Lions (7-8) from postseason consideration. They lost for the fifth time in six games, blowing fourth-quarter leads in each setback that might seal Jim Schwartz’s fate.

The embattled coach chose to play for overtime by running out the clock with 23 seconds and two timeouts left from the Detroit 25. When the crowd reacted with a chorus of boos, Schwartz turned his head toward the stands and appeared to angrily shout back at the fans.

Schwartz has lost nine straight games in December or January, leading to his job being in jeopardy.

RAMS 23, BUCCANEERS 13: ST. LOUIS (AP) — Robert Quinn got three of St. Louis’ seven sacks and set a franchise season record. Quinn leads the NFL with 18 sacks. He broke Kevin Carter’s franchise record of 17 in that 1999 Super Bowl title season.

Zac Stacy rushed for 104 yards on 33 carries and a touchdown, and the Rams (7-8) matched their victory total from last year. Fellow rookies Stedman Bailey scored on a 27-yard reverse, and Alec Ogletree forced two fumbles.

JETS 24, BROWNS 13: EAST RUTHERFORD, N.J. (AP) — Geno Smith threw two touchdown passes to David Nelson and ran for another score. Smith had his first game with at least two TD passes since October, with no turnovers or sacks. The rookie was 20 of 36 for 214 yards and also ran for 48 yards — including a 17-yard scoring scamper in the fourth quarter.

TITANS 20, JAGUARS 16: JACKSONVILLE, Fla. (AP) — Nate Washington scored on a 30-yard reception in the fourth quarter and Tennessee got a much-needed defensive stop late to end a three-game losing streak.

Tennessee (6-9) overcame a 10-point deficit in the second half and won for just the third time since September. Washington finished with six catches for 117 yards.