INDIANAPOLIS (AP) — Andrew Luck threw for three touchdowns and ran for another Sunday night, outplaying predecessor Peyton Manning in a 39-33 victory over the previously unbeaten Denver Broncos.

The victory ended the Broncos’ 17-game regular-season winning streak in the first game Manning played against his former team since being released in March 2012.

Manning finished 29 of 49 for 386 yards with three TDs and one interception. He was sacked four times and tried desperately to rally the Broncos late.

CHIEFS 17, TEXANS 16: KANSAS CITY, Mo. (AP) — Jamaal Charles ran for 86 yards and a touchdown, Alex Smith also ran for a score and the scrappy Chiefs held off the banged-up Houston to remain unbeaten.

The Chiefs were forced to punt the ball to Houston with 1:46 left in the game. But after Case Keenum threw an incompletion on first down, the young quarterback was stripped by linebacker Tamba Hali at his 2. Derrick Johnson recovered the fumble for the Chiefs.

REDSKINS 45, BEARS 41: LANDOVER, Md. (AP) — Roy Helu’s third touchdown, a 3-yard run with 45 seconds to play, lifted the Redskins.

Robert Griffin III completed 18 of 29 passes for 298 yards with two touchdowns and one interception for the Redskins (2-4), who have both of their wins against backup quarterbacks. This time it was Josh McCown, who entered in the second quarter after Jay Cutler left with a groin injury.

JETS 30,
PATRIOTS 27, OT:

 EAST RUTHERFORD, N.J. (AP) — Nick Folk kicked a 42-yard field goal with 5:07 left in overtime. Folk got a second chance after he missed a 56-yarder moments earlier. But Chris Jones was called for unsportsmanlike conduct for pushing a teammate forward to try to block the kick, a new NFL rule.

New York, given new life, ran the ball three times to set up Folk’s winner.

New England had defeated New York in six straight regular-season meetings, and saw its 12-game winning streak against the AFC East end.

STEELERS 19, RAVENS 16:

 PITTSBURGH (AP) — Shaun Suisham drilled a 42-yard field goal with no time remaining. Suisham’s fourth field goal of the day pushed the Steelers (2-4) to their second straight win.

Ben Roethlisberger completed 17 of 23 passes for 160 yards and a touchdown. He hit Antonio Brown for a pair of big gains on Pittsburgh’s final drive, putting Suisham well within range to win it. Running back Le’Veon Bell ran for a season-high 93 yards on 19 carries.

PACKERS 31,
BROWNS 13:

GREEN BAY, Wis. (AP) — Aaron Rodgers guided an undermanned offense with 260 yards and three touchdowns, and Eddie Lacy ran for another score.

Lacy finished with 82 yards, while tight end Jermichael Finley had a 10-yard touchdown catch in the first quarter before leaving with a neck injury. The team said he had movement in his extremities.

BENGALS 27, LIONS 24:

DETROIT (AP) — Mike Nugent’s 54-yard field goal as time expired lifted the Bengals. The AFC North-leading Bengals (5-2) won a game for the second straight week by the same score thanks to Nugent’s right foot. He made an overtime kick to give Cincinnati a win after it blew a 14-point, fourth-quarter lead at Buffalo

The Lions (4-3) looked like they did enough to send the game to OT, but rookie Sam Martin shanked a punt just 28 yards to midfield in the final minute.

COWBOYS 17,
EAGLES 3:

PHILADELPHIA (AP) — Tony Romo threw for 317 yards and one touchdown and the Cowboys overcame a sluggish start to take sole possession of first place in the NFC East.

The Eagles (3-4) have lost a franchise-worst nine straight games at home. Their last win at the Linc was over the New York Giants on Sept. 30, 2012.

FALCONS 31,
BUCCANEERS 23:

ATLANTA (AP) — Matt Ryan threw for 273 yards and three touchdowns, including two to Jacquizz Rodgers, and the Falcons snapped their three-game losing streak.

BILLS 23, DOLPHINS 21:

MIAMI GARDENS, Fla. (AP) — Mario Williams forced a fumble when he sacked Ryan Tannehill with less than three minutes left, setting up the winning field goal. Dan Carpenter, released in August after five seasons with the Dolphins, beat his former team by making a 31-yarder with 33 seconds to go.

PANTHERS 30, RAMS 15:

CHARLOTTE, N.C. (AP) — Cam Newton completed 15 of 17 passes for 204 yards and a touchdown in a heated game.

CHARGERS 24,
JAGUARS 6:

JACKSONVILLE, Fla. (AP) — Philip Rivers threw for 285 yards and a touchdown, Ryan Mathews ran for 110 yards and a score, and the surging Chargers (4-3) showed little, if any, issues with a short week, a cross-country flight and an early start time. And they played nothing like a team looking ahead to its bye week.

Then again, the Jaguars have made everyone look good