DENVER (AP) — In only the fourth meeting of teams 6-0 or better, Peyton Manning tied Brett Favre’s NFL record with his 186th regular-season win and Denver rattled Aaron Rodgers into one of the worst games of his career in the Broncos’ 29-10 victory over the Green Bay Packers on Sunday night.

Wearing the blue jerseys they did in beating the Packers for their first Super Bowl win in 1997, the Broncos piled it on in the fourth quarter, when DeMarcus Ware sacked Rodgers and the ball ended up in the end zone for a safety.

The Broncos improved to 7-0 for the first time since 1998, when they won the Super Bowl after finishing 14-2.

Rodgers was 14 of 22 for just 77 yards for the Packers (6-1) — the lowest of his career in a game where he wasn’t knocked out by injury.

Although neither quarterback threw for a touchdown, Manning was 21 of 29 for 340 yards. The Packers had only 140 yards of total offense to Denver’s 500.

SAINTS 52, GIANTS 49

NEW ORLEANS (AP) — Drew Brees passed for career highs of 511 yards and seven touchdowns, and recently signed Kai Forbath kicked a 50-yard field goal as time ran out, giving New Orleans the victory in a game with a record 13 scoring passes.

Eli Manning connected on a career-high six touchdown passes, three to fellow New Orleans native Odell Beckham Jr., but New York (4-4) fell for the second time in three games.

The 101 points tied for third most in NFL history. The teams combined for 1,030 yards.

Brandin Cooks and Willie Snead each had two touchdown catches for the Saints (4-4), who have won four of five after an 0-3 start. Brees’ other three touchdown passes went to Marques Colston, Ben Watson and C.J. Spiller, the last to tie the score at 49 with 36 seconds left.

BENGALS 16,

STEELERS 10

PITTSBURGH (AP) — Ben Roethlisberger’s return wasn’t enough to prevent the Bengals from getting off to their best start in franchise history.

Andy Dalton threw a touchdown pass with 2:57 to go, and the Bengals picked off Roethlisberger twice in the fourth quarter.

The Bengals are 7-0 for the first time and have a comfortable lead in their division.

The defending AFC North champion Steelers (4-4) hoped Roethlisberger’s return after missing four games with a sprained knee would kick-start them. After leading most of the game, they fall apart in the closing minutes.

Shawn Williams’ diving sideline interception at the Pittsburgh 45-yard line set up Dalton’s 9-yard touchdown pass to A.J. Green, who had another big game against the Steelers. He finished with 11 catches for 118 yards.

Reggie Nelson’s second interception set up Mike Nugent’s 44-yard field goal with 1:47 to go. The Steelers drove to the Cincinnati 16-yard line with 4 seconds left, but Roethlisberger’s pass went out of the end zone to finish it.

SEAHAWKS 13,

COWBOYS 12

ARLINGTON, Texas (AP) — Russell Wilson had a scoring pass for the game’s only touchdown and directed a late drive to the winning field goal, leading the defending NFC champions (4-4) back to .500 after an 0-2 start.

The Cowboys (2-5) lost their fifth straight without Tony Romo in Dez Bryant’s return from a five-game absence with a broken right foot.

The Seahawks started the decisive drive at their 15, with Wilson converting three third downs capped by a scramble that helped run the clock before Steven Hauschka’s 24-yard field goal with 1:06 remaining.

All of Dallas’ points came on Dan Bailey field goals.

Seattle receiver Ricardo Lockette had an injury scare and came away with a concussion and was moving his extremities after a vicious block by Jeff Heath on a punt return. Lockette was carted off the field after a lengthy delay.

BUCCANEERS 23,

FALCONS 20

ATLANTA (AP) — Bouncing back after blowing a 17-point lead, the Bucs got a 31-yard field goal from Connor Barth in the extra period to beat the mistake-prone Falcons.

Matt Ryan tied the game for the Falcons (6-2) on an 8-yard pass to Julio Jones with 17 seconds left in regulation. Having squandered a 24-point edge the previous week at Washington, the Bucs (3-4) were in trouble again.

Instead, Jameis Winston led an impressive drive on the first possession of OT, converting three times on third down before the drive stalled when he short-hopped a pass into the end zone for an open Adam Humphries. Barth made his third field goal of the game.

Atlanta got the ball but didn’t even make it to midfield. On fourth down, Ryan was heavily pressured by Gerald McCoy and Howard Jones, forcing a desperation pass that wasn’t close to anyone.

Despite four turnovers, the Falcons rallied from a 20-3 deficit, benefiting from a highly questionable decision by Tampa Bay coach Lovie Smith to go on fourth-and-1 at the Bucs 40 with 2 minutes to go.

CARDINALS 34, BROWNS 20

CLEVELAND (AP) — Carson Palmer threw for four touchdowns, three in the second half, and for 374 yards as Arizona rallied.

Palmer had two TD passes in the third quarter when the Cardinals (6-2) overcame a 20-10 halftime deficit. His third TD of the second half, a 6-yarder to Larry Fitzgerald, gave Arizona a 31-20 lead.

Michael Floyd had a 60-yard TD catch and tight end Troy Niklas had two short TD receptions as the Cardinals overcame four turnovers and won in Cleveland for the first time since 1985.

The Browns (2-6) dropped their third straight, and cornerback Joe Haden and safety Donte Whitner sustained concussions on consecutive plays in the third quarter; Cleveland lost two defenders and the lead in a span of 7:25.

VIKINGS 23, BEARS 20

CHICAGO (AP) — Adrian Peterson ran for 103 yards and Blair Walsh kicked a 36-yard field goal as time expired.

The Vikings had dropped seven straight at Soldier Field, and it looked like the streak would reach eight when Jay Cutler rolled to his right and plowed over safety Harrison Smith for a 4-yard touchdown with just under five minutes remaining. But two late scores lifted Minnesota (5-2) to its third straight win.

Stefon Diggs turned a short pass into a 40-yard TD when he spun around Sherrick McManis and went up the left side, tying it with 1:49 left.

After Chicago (2-5) punted, Teddy Bridgewater hit a leaping Charles Johnson for a 35-yard pass that put the ball on the 27. Two plays later Walsh booted the winner, pumping his right arm as the ball went through the uprights.

The Bears (2-5) lost star running back Matt Forte and receiver Eddie Royal to knee injuries while dropping their second straight game.

RAVENS 29,

CHARGERS 26

BALTIMORE (AP) — Justin Tucker kicked a 39-yard field goal on the final play. Joe Flacco threw for 319 yards and ran for a score to help Baltimore (2-6) snap a three-game skid and hand the Chargers (2-6) their fourth straight defeat.

The Ravens’ six losses this season have come by a combined 30 points, and their only win before Sunday came in overtime.

Tucker’s fifth field goal came three plays after a third-down pass interference call against Steve Williams moved the ball 21 yards to the San Diego 22.

The victory came at a price: Receiver Steve Smith tore his right Achilles tendon in the third quarter and is lost for the season. After being tackled at the end of an 18-yard gain, the 36-year-old Smith had to be helped off the field and could not put any weight on his right leg.

Now in his 15th NFL season, Smith has said he will retire after this year. He had five catches for 82 yards before the injury.

TEXANS 20, TITANS 6

HOUSTON (AP) — Brian Hoyer threw for 235 yards and two touchdowns, and Houston tied a franchise record with seven sacks.

A 21-yard touchdown reception by DeAndre Hopkins put Houston on top in the second quarter and the Texans (3-5) didn’t trail after that. Nate Washington’s 42-yard TD catch extended the lead.

Zach Mettenberger threw for 171 yards with an interception in his second straight start in place of rookie Marcus Mariota, who is out with a knee injury. Mettenberger was hurried and harassed all day to remain winless in eight career starts, with three losses against the Texans.

CHIEFS 45, LIONS 10

Alex Smith threw for 145 yards and two touchdowns, and ran for 78 yards and another TD to lead Kansas City over Detroit Lions at Wembley Stadium.

Smith scrambled his way through the Detroit defense for some big plays, including a career-high 49-yard run in the second quarter that set up his 12-yard touchdown run.

De’Anthony Thomas, Charcandrick West and Spencer Ware also rushed for touchdowns for the Chiefs. Thomas ended up with 100 total yards, while West ran for 97. Travis Kelce and Jeremy Maclin caught TD passes in the second half.